09 Control and Coordination - part 06 - Human Nervous System
09 Control and Coordination - part 06 - Human Nervous System
Human Nervous System :
Blood brain barrier (BBB) -
Always Remember :
- Nervous system in humans is well developed and complex.
- Broadly classified into three parts. viz,
- CNS
- PNS and
- ANS.
- The brain and spinal cord are the parts of CNS which lie along the mid dorsal axis.
- Brain is enclosed within the brain box/cranium of the skull, whereas the spinal cord occupies the vertebral canal of the vertebral column.
- Inner to these bony coverings, are three protective membranes called meninges that protect the brain and spinal cord.
- Outermost tough, non vascular, thick and fibrous meninx.
- Attached to the inner side of the cranium.
- Separated from the underlying arachnoid mater by the subdural space, filled with a serous fluid.
- Middle, thin and non vascular layer of connective tissue.
- Having web like appearance.
- Separated from the mater below by a narrow subarachnoid help in this process along with the astrocytes.
- space filled with cerebro spinal fluid - CSF.
- Innermost delicate, highly vascular membrane
- Lies in close contact with the CNS.
- Lymph like extra cellular fluid secreted by choroid plexuses of pia mater.
- Present inner to subarachnoid space in the ventricles of the brain within the central canal of spinal cord.
- Secreted by the pia mater, the choroid plexuses and the ependymal cells lining the ventricles of the brain and central canal of spinal cord.
- The three openings in the roof of medulla oblogata help in draining out the CSF from brain to the outside.
- The meninges and CSF act as a shock absorber.
- Protect the brain and spinal cord from mechanical injuries.
- Maintains constant pressure inside cranium.
- Helps in exchange of nutrients and wastes between blood and brain tissue.
- Helps in the supply of oxygen to the brain.
- Protects the brain from desiccation.
- Slightly alkaline fluid with a specific gravity of 1.005.
- A total of 100 -120 cc of CSF is present in and around the CNS.
- CSF is released by the pia mater.
- Inside the ventricles/cavities of the brain, there is release of CSF by the choroid plexuses and the ependymal cells.
Blood brain barrier (BBB) -
- Keeps a check on passage of ions and large molecules from the blood to the brain tissue.
- Endothelial cells lining the blood capillaries help in this process along with the astrocytes.
Always Remember :
- CSF is continuously generated by the ependymal cells lining the ventricles and central canal and simultaneoulsy drained out of the brain into the blood stream.
- CSF maintains a constant pressure inside the cranium.
- The nervous tissue is without lympatic vessels.
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